Turkish forces fired howitzer shells across the border into Syria's Ayn al Arab region on Wednesday, killing four Kurdish militants, state broadcaster TRT said.
The barrages were launched from Turkey's southeastern province of Şanlıurfa, along the Syrian border, TRT said. Six other militants were wounded in the strikes on the region, which is also known as Kobani.
It was the second time Turkey's army has shelled Kurdish militant positions east of the Euphrates. The attack came a day after Turkish President Recep Tayyip Erdoğan said Ankara has finalized plans for a "comprehensive and effective" operation to drive the Kurdish militants from the region.
People's Protection Units, or YPG, holds swathes of territory in Syria's north and northeast. Manbij is controlled by the SDF, an umbrella group dominated by the YPG.
The Syrian Democratic Forces (SDF) said it returned fire after Turkish forces targeted positions along the border.